Cerebrospinal fluid (empty) leakage is a widely recognized complication after neurosurgical procedures.
An important risk factor leading to increased morbidity, prolonged hospital stays, possible surgical revisions and increased costs.
represents the patient burden.1,2 Incidence rates vary depending on age, indication, site of operation and underlying pathology, but
total void leakage occurs in 4-32% of surgical cases.3,4
Providing waterproof dural closure to ensure effective control of Achieving Bos leakage
it is a difficult job. Puncture from a single needle is sufficient to cause leakage and during prolonged surgical procedures, fragile
The dura mater shrinks due to dehydration, making closure more difficult.
Effective dural sealants should reduce the risk of liquor leakage after cranial surgery by increasing dural closure. With this
However, a recent Review found that the only commercially available dural sealants available
demonstrated that it does not substantially reduce postoperative bos leakage compared to sutures per head (respectively
8.2% versus 8.4%) .3